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Human pluripotent stem-cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing

Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human models that recapitulate disease pathophysiology. In this study, we generated alveolar organoids (AOs) derived from human pluripotent stem cells...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Hyun, An, Geun Ho, Kim, Ji-Young, Rasaei, Roya, Kim, Woo Jin, Jin, Xiong, Woo, Dong-Hun, Han, Choongseong, Yang, Se-Ran, Kim, Jong-Hoon, Hong, Seok-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961057/
https://www.ncbi.nlm.nih.gov/pubmed/33723255
http://dx.doi.org/10.1038/s41420-021-00439-7