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The effect of nerve growth factor on supporting spatial memory depends upon hippocampal cholinergic innervation

Nerve growth factor (NGF) gene therapy has been used in clinical trials of Alzheimer’s disease. Understanding the underlying mechanisms of how NGF influences memory may help develop new strategies for treatment. Both NGF and the cholinergic system play important roles in learning and memory. NGF is...

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Detalles Bibliográficos
Autores principales: Eu, Wei Zheng, Chen, Yu-Ju, Chen, Wei-Ting, Wu, Kuan-Yu, Tsai, Cheng-Yu, Cheng, Sin-Jhong, Carter, Roderick N., Huang, Guo-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961060/
https://www.ncbi.nlm.nih.gov/pubmed/33723225
http://dx.doi.org/10.1038/s41398-021-01280-3