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The effect of nerve growth factor on supporting spatial memory depends upon hippocampal cholinergic innervation
Nerve growth factor (NGF) gene therapy has been used in clinical trials of Alzheimer’s disease. Understanding the underlying mechanisms of how NGF influences memory may help develop new strategies for treatment. Both NGF and the cholinergic system play important roles in learning and memory. NGF is...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961060/ https://www.ncbi.nlm.nih.gov/pubmed/33723225 http://dx.doi.org/10.1038/s41398-021-01280-3 |