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Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

Mass spectrometry imaging (MSI) visualizes molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labeling provided spatial analyses of phosphatidylcholine (PC) metabolism in mouse lungs. Dysre...

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Detalles Bibliográficos
Autores principales: Ellis, Shane R., Hall, Emily, Panchal, Madhuriben, Flinders, Bryn, Madsen, Jens, Koster, Grielof, Heeren, Ron.M.A., Clark, Howard W., Postle, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961103/
https://www.ncbi.nlm.nih.gov/pubmed/33453219
http://dx.doi.org/10.1016/j.jlr.2021.100023