Cargando…

Rewiring of purine metabolism in response to acidosis stress in glioma stem cells

Glioma stem cells (GSCs) contribute to therapy resistance and poor outcomes for glioma patients. A significant feature of GSCs is their ability to grow in an acidic microenvironment. However, the mechanism underlying the rewiring of their metabolism in low pH remains elusive. Here, using metabolomic...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Xiaoyu, Wang, Liping, Zang, Qingce, Li, Shanshan, Li, Limei, Wang, Zhixing, He, Jiuming, Qiang, Boqin, Han, Wei, Zhang, Ruiping, Peng, Xiaozhong, Abliz, Zeper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961141/
https://www.ncbi.nlm.nih.gov/pubmed/33723244
http://dx.doi.org/10.1038/s41419-021-03543-9