Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models

Trichloroethylene (TCE) is an industrial solvent and widespread environmental contaminant. Although TCE exposure is prevalent, epidemiological studies of TCE exposure associations with adverse birth outcomes are inconclusive. Prior studies show that the TCE metabolite S-(1,2-dichlorovinyl)-l-cystein...

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Detalles Bibliográficos
Autores principales: Elkin, Elana R., Bakulski, Kelly M., Colacino, Justin A., Bridges, Dave, Kilburn, Brian A., Armant, D. Randall, Loch-Caruso, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Toxicogenomics and Omics Technologies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961173/
https://www.ncbi.nlm.nih.gov/pubmed/33725128
http://dx.doi.org/10.1007/s00204-021-03011-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961173/
https://www.ncbi.nlm.nih.gov/pubmed/33725128
http://dx.doi.org/10.1007/s00204-021-03011-5

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