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COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial

OBJECTIVES: The main goal of the COVIDENZA trial is to evaluate if inhibition of testosterone signalling by enzalutamide can improve the outcome of patients hospitalised for COVID-19. The hypothesis is based on the observation that the majority of patients in need of intensive care are male, and the...

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Detalles Bibliográficos
Autores principales: Welén, Karin, Överby, Anna K, Ahlm, Clas, Freyhult, Eva, Robinsson, David, Henningsson, Anna Jonsson, Stranne, Johan, Bremell, Daniel, Angelin, Martin, Lindquist, Elisabeth, Buckland, Robert, Carlsson, Camilla Thellenberg, Pauksens, Karlis, Bill-Axelsson, Anna, Akre, Olof, Ryden, Cecilia, Wagenius, Magnus, Bjartell, Anders, Nilsson, Anna C., Styrke, Johan, Repo, Johanna, Balkhed, Åse Östholm, Niward, Katarina, Gisslén, Magnus, Josefsson, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961321/
https://www.ncbi.nlm.nih.gov/pubmed/33726804
http://dx.doi.org/10.1186/s13063-021-05137-4