Insights into the Mechanism and Catalysis of Peptide Thioester Synthesis by Alkylselenols Provide a New Tool for Chemical Protein Synthesis

While thiol-based catalysts are widely employed for chemical protein synthesis relying on peptide thioester chemistry, this is less true for selenol-based catalysts whose development is in its infancy. In this study, we compared different selenols derived from the selenocysteamine scaffold for their...

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Detalles Bibliográficos
Autores principales: Kerdraon, Florent, Bogard, Gemma, Snella, Benoît, Drobecq, Hervé, Pichavant, Muriel, Agouridas, Vangelis, Melnyk, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961367/
https://www.ncbi.nlm.nih.gov/pubmed/33806630
http://dx.doi.org/10.3390/molecules26051386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961367/
https://www.ncbi.nlm.nih.gov/pubmed/33806630
http://dx.doi.org/10.3390/molecules26051386

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