The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory

Microglia, the innate immune cells of the CNS, exhibit long-term response changes indicative of innate immune memory (IIM). Our previous studies revealed IIM patterns of microglia with opposing immune phenotypes: trained immunity after a low dose and immune tolerance after a high dose challenge with...

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Detalles Bibliográficos
Autores principales: Lajqi, Trim, Marx, Christian, Hudalla, Hannes, Haas, Fabienne, Große, Silke, Wang, Zhao-Qi, Heller, Regine, Bauer, Michael, Wetzker, Reinhard, Bauer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961448/
https://www.ncbi.nlm.nih.gov/pubmed/33806610
http://dx.doi.org/10.3390/ijms22052578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961448/
https://www.ncbi.nlm.nih.gov/pubmed/33806610
http://dx.doi.org/10.3390/ijms22052578

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