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Heat-Inactivation of Human Serum Destroys C1 Inhibitor, Pro-motes Immune Complex Formation, and Improves Human T Cell Function

Heat-inactivation of sera is used to reduce possible disturbing effects of complement factors in cell-culture experiments, but it is controversially discussed whether this procedure is appropriate or could be neglected. Here, we report a strong impact of heat-inactivation of human sera on the activa...

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Detalles Bibliográficos
Autores principales: Fante, Matthias A., Decking, Sonja-Maria, Bruss, Christina, Schreml, Stephan, Siska, Peter J., Kreutz, Marina, Renner, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961502/
https://www.ncbi.nlm.nih.gov/pubmed/33808005
http://dx.doi.org/10.3390/ijms22052646