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Parking CAR T Cells in Tumours: Oncolytic Viruses as Valets or Vandals?

SIMPLE SUMMARY: Chimeric Antigen Receptor (CAR) modified T cell therapy has revolutionized the treatment of B cell malignancies, however transposition of the technology to the solid tumour setting has been met with more therapeutic resistance. Oncolytic Viruses (OVs) are multi-modal agents, possessi...

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Detalles Bibliográficos
Autores principales: Evgin, Laura, Vile, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961585/
https://www.ncbi.nlm.nih.gov/pubmed/33807553
http://dx.doi.org/10.3390/cancers13051106