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Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine

Nevirapine (NVP), a non-nucleoside reverse transcriptase inhibitor widely used in combined antiretroviral therapy and to prevent mother-to-child transmission of the human immunodeficiency virus type 1, is associated with several adverse side effects. Using 12-mesyloxy-nevirapine, a model electrophil...

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Detalles Bibliográficos
Autores principales: Harjivan, Shrika G., Charneira, Catarina, Martins, Inês L., Pereira, Sofia A., Espadas, Guadalupe, Sabidó, Eduard, Beland, Frederick A., Marques, M. Matilde, Antunes, Alexandra M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961589/
https://www.ncbi.nlm.nih.gov/pubmed/33802579
http://dx.doi.org/10.3390/molecules26051349