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Sitosterolemia: Twenty Years of Discovery of the Function of ABCG5 ABCG8

Sitosterolemia is a lipid disorder characterized by the accumulation of dietary xenosterols in plasma and tissues caused by mutations in either ABCG5 or ABCG8. ABCG5 ABCG8 encodes a pair of ABC half transporters that form a heterodimer (G5G8), which then traffics to the surface of hepatocytes and en...

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Detalles Bibliográficos
Autores principales: Williams, Kori, Segard, Allison, Graf, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961684/
https://www.ncbi.nlm.nih.gov/pubmed/33807969
http://dx.doi.org/10.3390/ijms22052641