Inhibition of Phosphodiesterase-4 in Psoriatic Arthritis and Inflammatory Bowel Diseases

Phosphodiesterases (PDEs) are a heterogeneous superfamily of enzymes which catalyze the degradation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Among PDEs, PDE4 is the most widely studied and characterized isoenzyme. PDE4 bl...

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Detalles Bibliográficos
Autores principales: Picchianti-Diamanti, Andrea, Spinelli, Francesca Romana, Rosado, Maria Manuela, Conti, Fabrizio, Laganà, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961737/
https://www.ncbi.nlm.nih.gov/pubmed/33807944
http://dx.doi.org/10.3390/ijms22052638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961737/
https://www.ncbi.nlm.nih.gov/pubmed/33807944
http://dx.doi.org/10.3390/ijms22052638

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