Semi-Synthesis of Harringtonolide Derivatives and Their Antiproliferative Activity

Harringtonolide (HO), a natural product isolated from Cephalotaxus harringtonia, exhibits potent antiproliferative activity. However, little information has been reported on the systematic structure−activity relationship (SAR) of HO derivatives. Modifications on tropone, lactone, and allyl positions...

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Detalles Bibliográficos
Autores principales: Wu, Xiutao, Gong, Lijie, Chen, Chen, Tao, Ye, Zhou, Wuxi, Kong, Lingyi, Luo, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961763/
https://www.ncbi.nlm.nih.gov/pubmed/33806554
http://dx.doi.org/10.3390/molecules26051380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961763/
https://www.ncbi.nlm.nih.gov/pubmed/33806554
http://dx.doi.org/10.3390/molecules26051380

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