PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway

Mitochondrial apoptosis is one of the main mechanisms for cancer cells to overcome chemoresistance. Hexokinase 2 (HK2) can resist cancer cell apoptosis by expressing on mitochondria and binding to voltage-dependent anion channel 1 (VDAC1). We previously reported that peroxisome proliferator-activate...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yanqing, Kang, Jinsong, Fu, Jiaying, Luo, Haoge, Liu, Yanan, Li, Yang, Sun, Liankun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961780/
https://www.ncbi.nlm.nih.gov/pubmed/33802591
http://dx.doi.org/10.3390/ijms22052537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961780/
https://www.ncbi.nlm.nih.gov/pubmed/33802591
http://dx.doi.org/10.3390/ijms22052537

Ejemplares similares