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PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway

Mitochondrial apoptosis is one of the main mechanisms for cancer cells to overcome chemoresistance. Hexokinase 2 (HK2) can resist cancer cell apoptosis by expressing on mitochondria and binding to voltage-dependent anion channel 1 (VDAC1). We previously reported that peroxisome proliferator-activate...

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Detalles Bibliográficos
Autores principales:	Li, Yanqing, Kang, Jinsong, Fu, Jiaying, Luo, Haoge, Liu, Yanan, Li, Yang, Sun, Liankun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961780/ https://www.ncbi.nlm.nih.gov/pubmed/33802591 http://dx.doi.org/10.3390/ijms22052537

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