Structural Basis for the Functional Changes by EGFR Exon 20 Insertion Mutations

SIMPLE SUMMARY: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer that claims the lives of many worldwide. Activating mutations occurring on the epidermal growth factor receptor (EGFR) protein have been associated with the pathogenesis of NSCLC, among which exon 20 insertion...

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Detalles Bibliográficos
Autores principales: Tamirat, Mahlet Z., Kurppa, Kari J., Elenius, Klaus, Johnson, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961794/
https://www.ncbi.nlm.nih.gov/pubmed/33807850
http://dx.doi.org/10.3390/cancers13051120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961794/
https://www.ncbi.nlm.nih.gov/pubmed/33807850
http://dx.doi.org/10.3390/cancers13051120

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