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CReVIS-Seq: A highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites

Lentiviruses have been widely used as a means of transferring exogenous DNAs into human cells to treat various genetic diseases. Lentiviral vectors are fundamentally integrated into the host genome, but their integration sites are generally unpredictable, which may increase the uncertainty for their...

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Detalles Bibliográficos
Autores principales: Kim, Heon Seok, Hwang, Gue-Ho, Lee, Hyomin K., Bae, Taegeun, Park, Seong-Ho, Kim, Yong Jun, Lee, Sun, Park, Jae-Hoon, Bae, Sangsu, Hur, Junho K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961857/
https://www.ncbi.nlm.nih.gov/pubmed/33768124
http://dx.doi.org/10.1016/j.omtm.2020.10.012