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Dispirooxindoles Based on 2-Selenoxo-Imidazolidin-4-Ones: Synthesis, Cytotoxicity and ROS Generation Ability

A regio- and diastereoselective synthesis of two types of dispiro derivatives of 2-selenoxoimidazolidin-4-ones, differing in the position of the nitrogen atom in the central pyrrolidine ring of the spiro-fused system—namely, 2-selenoxodispiro[imidazolidine-4,3′-pyrrolidine-2′,3″-indoline]-2″,5-dione...

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Detalles Bibliográficos
Autores principales: Novotortsev, Vladimir K., Kukushkin, Maxim E., Tafeenko, Viktor A., Skvortsov, Dmitry A., Kalinina, Marina A., Timoshenko, Roman V., Chmelyuk, Nelly S., Vasilyeva, Liliya A., Tarasevich, Boris N., Gorelkin, Petr V., Erofeev, Alexander S., Majouga, Alexander G., Zyk, Nikolai V., Beloglazkina, Elena K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961907/
https://www.ncbi.nlm.nih.gov/pubmed/33807662
http://dx.doi.org/10.3390/ijms22052613