Expression of Interferons Lambda 3 and 4 Induces Identical Response in Human Liver Cell Lines Depending Exclusively on Canonical Signaling

Lambda interferons mediate antiviral immunity by inducing interferon-stimulated genes (ISGs) in epithelial tissues. A common variant rs368234815TT/∆G creating functional gene from an IFNL4 pseudogene is associated with the expression of major ISGs in the liver but impaired clearance of hepatitis C....

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Detalles Bibliográficos
Autores principales: Lunova, Mariia, Kubovciak, Jan, Smolková, Barbora, Uzhytchak, Mariia, Michalova, Kyra, Dejneka, Alexandr, Strnad, Pavel, Lunov, Oleg, Jirsa, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961969/
https://www.ncbi.nlm.nih.gov/pubmed/33806448
http://dx.doi.org/10.3390/ijms22052560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961969/
https://www.ncbi.nlm.nih.gov/pubmed/33806448
http://dx.doi.org/10.3390/ijms22052560

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