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Dual Targeting of CDK4/6 and cMET in Metastatic Uveal Melanoma

SIMPLE SUMMARY: Up to 50% of uveal melanoma patients subsequently develop metastases, for which no effective treatment has been identified. In this study, 87.5% of uveal melanoma patients’ samples were positive for phosphorylated retinoblastoma (RB), and ex vivo incubation of patients’ biopsy specim...

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Detalles Bibliográficos
Autores principales: Ohara, Masahiro, Saito, Kengo, Kageyama, Ken, Terai, Mizue, Cheng, Hanyin, Aplin, Andrew E., Sato, Takami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961994/
https://www.ncbi.nlm.nih.gov/pubmed/33806615
http://dx.doi.org/10.3390/cancers13051104