Nucleophilic Aromatic Substitution of Polyfluoroarene to Access Highly Functionalized 10-Phenylphenothiazine Derivatives

Nucleophilic aromatic substitution (S(N)Ar) reactions can provide metal-free access to synthesize monosubstituted aromatic compounds. We developed efficient S(N)Ar conditions for p-selective substitution of polyfluoroarenes with phenothiazine in the presence of a mild base to afford the correspondin...

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Detalles Bibliográficos
Autores principales: Kikushima, Kotaro, Koyama, Haruka, Kodama, Kazuki, Dohi, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962002/
https://www.ncbi.nlm.nih.gov/pubmed/33806360
http://dx.doi.org/10.3390/molecules26051365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962002/
https://www.ncbi.nlm.nih.gov/pubmed/33806360
http://dx.doi.org/10.3390/molecules26051365

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