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Nucleophilic Aromatic Substitution of Polyfluoroarene to Access Highly Functionalized 10-Phenylphenothiazine Derivatives
Nucleophilic aromatic substitution (S(N)Ar) reactions can provide metal-free access to synthesize monosubstituted aromatic compounds. We developed efficient S(N)Ar conditions for p-selective substitution of polyfluoroarenes with phenothiazine in the presence of a mild base to afford the correspondin...
Autores principales: | Kikushima, Kotaro, Koyama, Haruka, Kodama, Kazuki, Dohi, Toshifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962002/ https://www.ncbi.nlm.nih.gov/pubmed/33806360 http://dx.doi.org/10.3390/molecules26051365 |
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