ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization

ATP13A2, a late endo-/lysosomal polyamine transporter, is implicated in a variety of neurodegenerative diseases, including Parkinson’s disease and Kufor–Rakeb syndrome, an early-onset atypical form of parkinsonism. Loss-of-function mutations in ATP13A2 result in lysosomal deficiency as a consequence...

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Detalles Bibliográficos
Autores principales: Si, Jianmin, Van den Haute, Chris, Lobbestael, Evy, Martin, Shaun, van Veen, Sarah, Vangheluwe, Peter, Baekelandt, Veerle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962109/
https://www.ncbi.nlm.nih.gov/pubmed/33799982
http://dx.doi.org/10.3390/ijms22052689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962109/
https://www.ncbi.nlm.nih.gov/pubmed/33799982
http://dx.doi.org/10.3390/ijms22052689

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