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Escin inhibits angiogenesis by suppressing interleukin-8 and vascular endothelial growth factor production by blocking nuclear factor-κB activation in pancreatic cancer cell lines

Pancreatic cancer (PaCa) is one of the most aggressive types of cancer. Thus, the development of new and more effective therapies is urgently required. Escin, a pentacyclic triterpenoid from the horse chestnut, has been reported to exhibit antitumor potential by reducing cell proliferation and block...

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Detalles Bibliográficos
Autores principales: Omi, Kan, Matsuo, Yoichi, Ueda, Goro, Aoyama, Yoshinaga, Kato, Tomokatsu, Hayashi, Yuichi, Imafuji, Hiroyuki, Saito, Kenta, Tsuboi, Ken, Morimoto, Mamoru, Ogawa, Ryo, Takahashi, Hiroki, Takiguchi, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962110/
https://www.ncbi.nlm.nih.gov/pubmed/33760162
http://dx.doi.org/10.3892/or.2021.8006