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Excision of Oxidatively Generated Guanine Lesions by Competitive DNA Repair Pathways

The base and nucleotide excision repair pathways (BER and NER, respectively) are two major mechanisms that remove DNA lesions formed by the reactions of genotoxic intermediates with cellular DNA. It is generally believed that small non-bulky oxidatively generated DNA base modifications are removed b...

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Detalles Bibliográficos
Autores principales: Shafirovich, Vladimir, Geacintov, Nicholas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962115/
https://www.ncbi.nlm.nih.gov/pubmed/33800059
http://dx.doi.org/10.3390/ijms22052698