Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing

Transient delivery of CRISPR‐based genome editing effectors is important to reduce off‐target effects and immune responses. Recently extracellular vesicles (EVs) have been explored for Cas9 ribonucleoprotein (RNP) delivery. However, lack of mechanisms to enrich RNPs into EVs limited the efficiency o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Xingang, Lyu, Pin, Yoo, Kyung, Yadav, Manish Kumar, Singh, Ravi, Atala, Anthony, Lu, Baisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962171/
https://www.ncbi.nlm.nih.gov/pubmed/33747370
http://dx.doi.org/10.1002/jev2.12076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962171/
https://www.ncbi.nlm.nih.gov/pubmed/33747370
http://dx.doi.org/10.1002/jev2.12076

Ejemplares similares