Design, Synthesis and Pharmacological Evaluation of Three Novel Dehydroabietyl Piperazine Dithiocarbamate Ruthenium (II) Polypyridyl Complexes as Potential Antitumor Agents: DNA Damage, Cell Cycle Arrest and Apoptosis Induction

The use of cisplatin is severely limited by its toxic side-effects, which has spurred chemists to employ different strategies in the development of new metal-based anticancer agents. Here, three novel dehydroabietyl piperazine dithiocarbamate ruthenium (II) polypyridyl complexes (6a–6c) were synthes...

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Detalles Bibliográficos
Autores principales: Wang, Haoran, Wei, Jianhua, Jiang, Hong, Zhang, Ye, Jiang, Caina, Ma, Xianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962184/
https://www.ncbi.nlm.nih.gov/pubmed/33800091
http://dx.doi.org/10.3390/molecules26051453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962184/
https://www.ncbi.nlm.nih.gov/pubmed/33800091
http://dx.doi.org/10.3390/molecules26051453

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