The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma

BACKGROUND: Neuroblastoma is a childhood neural crest tumor showing large clinical and genetic heterogeneity, one form displaying 11q-deletion is very aggressive. It has been shown that 11q-deletion results in decreased expression of DLG2, a gene residing in the deleted region. DLG2 has a number of...

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Detalles Bibliográficos
Autores principales: Keane, Simon, Martinsson, Tommy, Kogner, Per, Ejeskär, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962242/
https://www.ncbi.nlm.nih.gov/pubmed/33726762
http://dx.doi.org/10.1186/s12935-021-01851-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962242/
https://www.ncbi.nlm.nih.gov/pubmed/33726762
http://dx.doi.org/10.1186/s12935-021-01851-w

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