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α(1A)-adrenaline receptors in dorsal horn inhibitory neurons have an inhibitory role in the regulation of chloroquine-induced itch in mice

Our previous study showed the intrinsic ability of descending noradrenergic neurons projecting from the locus coeruleus to the spinal dorsal horn (SDH) to suppress itch-related behaviors. Noradrenaline and α(1A)-adrenaline receptor (α(1A)-AR) agonist increase inhibitory synaptic inputs onto SDH inte...

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Detalles Bibliográficos
Autores principales: Shiraishi, Yuto, Koga, Keisuke, Yamagata, Ryo, Hatada, Izuho, Shiratori-Hayashi, Miho, Tsuda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962300/
https://www.ncbi.nlm.nih.gov/pubmed/33726812
http://dx.doi.org/10.1186/s13041-021-00768-9