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Extracellular vesicles derived from EphB2-overexpressing bone marrow mesenchymal stem cells ameliorate DSS-induced colitis by modulating immune balance

BACKGROUND: The bone marrow mesenchymal stem cell (BMSCs)-derived extracellular vesicles (EVs) open up a new avenue for ulcerative colitis (UC) treatment recently, but they are not selectively enriched in targeted tissues. EphB2, a cell-to-cell signaling receptor, is identified as a regulator for in...

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Detalles Bibliográficos
Autores principales: Yu, Ting, Chu, Si, Liu, Xingxing, Li, Junyi, Chen, Qianyun, Xu, Meng, Wu, Hui, Li, Mingyue, Dong, Yalan, Zhu, Feng, Zhou, Haifeng, Hu, Desheng, Fan, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962309/
https://www.ncbi.nlm.nih.gov/pubmed/33722292
http://dx.doi.org/10.1186/s13287-021-02232-w