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Extracellular vesicles derived from EphB2-overexpressing bone marrow mesenchymal stem cells ameliorate DSS-induced colitis by modulating immune balance
BACKGROUND: The bone marrow mesenchymal stem cell (BMSCs)-derived extracellular vesicles (EVs) open up a new avenue for ulcerative colitis (UC) treatment recently, but they are not selectively enriched in targeted tissues. EphB2, a cell-to-cell signaling receptor, is identified as a regulator for in...
Autores principales: | Yu, Ting, Chu, Si, Liu, Xingxing, Li, Junyi, Chen, Qianyun, Xu, Meng, Wu, Hui, Li, Mingyue, Dong, Yalan, Zhu, Feng, Zhou, Haifeng, Hu, Desheng, Fan, Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962309/ https://www.ncbi.nlm.nih.gov/pubmed/33722292 http://dx.doi.org/10.1186/s13287-021-02232-w |
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