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Secreted factors from dental pulp stem cells improve Sjögren’s syndrome via regulatory T cell-mediated immunosuppression

BACKGROUND: Sjögren’s syndrome (SS) is a chronic autoimmune disease primarily characterized by inflammation in the salivary and lacrimal glands. Activated T cells contribute to disease pathogenesis by producing proinflammatory cytokines, which leads to a positive feedback loop establishment. The stu...

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Detalles Bibliográficos
Autores principales: Matsumura-Kawashima, Mayu, Ogata, Kenichi, Moriyama, Masafumi, Murakami, Yuka, Kawado, Tatsuya, Nakamura, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962357/
https://www.ncbi.nlm.nih.gov/pubmed/33726818
http://dx.doi.org/10.1186/s13287-021-02236-6