Cargando…

Secreted factors from dental pulp stem cells improve Sjögren’s syndrome via regulatory T cell-mediated immunosuppression

BACKGROUND: Sjögren’s syndrome (SS) is a chronic autoimmune disease primarily characterized by inflammation in the salivary and lacrimal glands. Activated T cells contribute to disease pathogenesis by producing proinflammatory cytokines, which leads to a positive feedback loop establishment. The stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsumura-Kawashima, Mayu, Ogata, Kenichi, Moriyama, Masafumi, Murakami, Yuka, Kawado, Tatsuya, Nakamura, Seiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962357/ https://www.ncbi.nlm.nih.gov/pubmed/33726818 http://dx.doi.org/10.1186/s13287-021-02236-6

Ejemplares similares

Dental pulp-derived stem cell-conditioned media attenuates secondary Sjögren's syndrome via suppression of inflammatory cytokines in the submandibular glands
por: Ogata, Kenichi, et al.
Publicado: (2021)

The Therapeutic Potential of Secreted Factors from Dental Pulp Stem Cells for Various Diseases
por: Ogata, Kenichi, et al.
Publicado: (2022)

Cytokine Mixtures Mimicking Secretomes From Mesenchymal Stem Cells Improve Medication‐Related Osteonecrosis of the Jaw in a Rat Model
por: Ogata, Kenichi, et al.
Publicado: (2017)

Cytotoxic CD8(+) T cells may be drivers of tissue destruction in Sjögren’s syndrome
por: Kaneko, Naoki, et al.
Publicado: (2022)

Tissue-infiltrating immune cells contribute to understanding the pathogenesis of Kimura disease: A case report
por: Maehara, Takashi, et al.
Publicado: (2019)

Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients
por: Maehara, T, et al.
Publicado: (2012)

Successful Treatment of Protein-Losing Gastroenteropathy with Steroid Pulse and Immunosuppressive Therapies in a Patient with Sjögren Syndrome
por: Nasu, Tetsushi, et al.
Publicado: (2011)

The Molecular Mechanisms of Regulatory T Cell Immunosuppression
por: Pandiyan, Pushpa, et al.
Publicado: (2011)

The molecular mechanisms of regulatory T cell immunosuppression
por: Smith, Kendall A.
Publicado: (2012)

Immunosuppressive Mechanisms of Regulatory B Cells
por: Catalán, Diego, et al.
Publicado: (2021)

Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study
por: Nakashima, Misako, et al.
Publicado: (2017)

Effectiveness of imaging modalities for screening IgG4-related dacryoadenitis and sialadenitis (Mikulicz’s disease) and for differentiating it from Sjögren’s syndrome (SS), with an emphasis on sonography
por: Shimizu, Mayumi, et al.
Publicado: (2015)

Toll-like receptor 9-positive plasmacytoid dendritic cells promote Th17 immune responses in oral lichen planus stimulated by epithelium-derived cathepsin K
por: Miyahara, Yuka, et al.
Publicado: (2023)

Angiogenesis during coronal pulp regeneration using rat dental pulp cells: Neovascularization in rat molars in vivo and proangiogenic dental pulp cell-endothelial cell interactions in vitro
por: Zaw, Zar Chi Thein, et al.
Publicado: (2022)

The Role of Regulatory T Cells in the Onset and Progression of Primary Sjögren’s Syndrome
por: Blinova, Varvara G., et al.
Publicado: (2023)

Altered subgroups of regulatory T cells in patients with primary Sjögren's syndrome
por: Lin, Jing-Chi, et al.
Publicado: (2023)

Direct Comparison of Therapeutic Effects on Diabetic Polyneuropathy between Transplantation of Dental Pulp Stem Cells and Administration of Dental Pulp Stem Cell-Secreted Factors
por: Kanada, Saki, et al.
Publicado: (2020)

Unique Phenotypes and Functions of Follicular Helper T Cells and Regulatory T Cells in Sjögren’s Syndrome
por: Saito, Masako, et al.
Publicado: (2018)

Tumor cell secretion of soluble factor(s) for specific immunosuppression
por: Kano, Arihiro
Publicado: (2015)

T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives
por: Alunno, Alessia, et al.
Publicado: (2015)

The effect of different pulp-capping materials on proliferation, migration and cytokine secretion of human dental pulp stem cells
por: Omidi, Salma, et al.
Publicado: (2020)

Review of a novel disease entity, immunoglobulin G4-related disease
por: Maehara, Takashi, et al.
Publicado: (2020)

Comparison of telomere length and association with progenitor cell markers in lacrimal gland between Sjögren syndrome and non-Sjögren syndrome dry eye patients
por: Kawashima, Motoko, et al.
Publicado: (2011)

Peripheral regulatory cells immunophenotyping in Primary Sjögren's Syndrome: a cross-sectional study
por: Furuzawa-Carballeda, Janette, et al.
Publicado: (2013)

Cytokine/chemokine profiles contribute to understanding the pathogenesis and diagnosis of primary Sjögren's syndrome
por: Moriyama, M, et al.
Publicado: (2012)

Comparison of performance of the 2016 ACR-EULAR classification criteria for primary Sjögren's syndrome with other sets of criteria in Japanese patients
por: Tsuboi, Hiroto, et al.
Publicado: (2017)

Cell Contact–Dependent Immunosuppression by Cd4(+)Cd25(+)Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β
por: Nakamura, Kazuhiko, et al.
Publicado: (2001)

Ellagic Acid Suppresses ApoB Secretion and Enhances ApoA-1 Secretion from Human Hepatoma Cells, HepG2
por: Ieda, Ayana, et al.
Publicado: (2021)

Secreted factors from dental pulp stem cells improve glucose intolerance in streptozotocin-induced diabetic mice by increasing pancreatic β-cell function
por: Izumoto-Akita, Takako, et al.
Publicado: (2015)

‘Hardcore’ OX40(+) immunosuppressive regulatory T cells in hepatic cirrhosis and cancer
por: Piconese, Silvia, et al.
Publicado: (2014)

Contribution of regulatory T cells to immunosuppression and disease progression in multiple myeloma patients
por: Raja, Karthick Raja Muthu, et al.
Publicado: (2013)

Lenalidomide overcomes the immunosuppression of regulatory CD8(+)CD28(−) T-cells
por: Neuber, Brigitte, et al.
Publicado: (2017)

Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells
por: Xing, Shaojun, et al.
Publicado: (2019)

Human Dental Pulp Stem Cells Differentiate into Cementoid-Like-Secreting Cells on Decellularized Teeth Scaffolds
por: Mata, Manuel, et al.
Publicado: (2022)

Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells
por: Sonoda, Soichiro, et al.
Publicado: (2016)

Dendritic cells matured in the presence of TLR ligands overcome the immunosuppressive functions of regulatory T cells
por: Berk, Erik, et al.
Publicado: (2014)

Circulating Immunosuppressive Regulatory T Cells Predict Risk of Incident Cutaneous Squamous Cell Carcinoma
por: Rollison, Dana E., et al.
Publicado: (2021)

Immune checkpoint blockade impairs immunosuppressive mechanisms of regulatory T cells in B-cell lymphoma
por: Bauer, Vera, et al.
Publicado: (2021)

Oral Squamous Cell Carcinoma Contributes to Differentiation of Monocyte-Derived Tumor-Associated Macrophages via PAI-1 and IL-8 Production
por: Kai, Kazuki, et al.
Publicado: (2021)

Mesenchymal Stromal Cell Secretion of Programmed Death‐1 Ligands Regulates T Cell Mediated Immunosuppression
por: Davies, Lindsay C., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_e8vcr5qs6pqcf7d530v0d9l96v