Histone lactylation drives oncogenesis by facilitating m(6)A reader protein YTHDF2 expression in ocular melanoma

BACKGROUND: Histone lactylation, a metabolic stress-related histone modification, plays an important role in the regulation of gene expression during M1 macrophage polarization. However, the role of histone lactylation in tumorigenesis remains unclear. RESULTS: Here, we show histone lactylation is e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jie, Chai, Peiwei, Xie, Minyue, Ge, Shengfang, Ruan, Jing, Fan, Xianqun, Jia, Renbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962360/
https://www.ncbi.nlm.nih.gov/pubmed/33726814
http://dx.doi.org/10.1186/s13059-021-02308-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962360/
https://www.ncbi.nlm.nih.gov/pubmed/33726814
http://dx.doi.org/10.1186/s13059-021-02308-z

Ejemplares similares