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Histone lactylation drives oncogenesis by facilitating m(6)A reader protein YTHDF2 expression in ocular melanoma

BACKGROUND: Histone lactylation, a metabolic stress-related histone modification, plays an important role in the regulation of gene expression during M1 macrophage polarization. However, the role of histone lactylation in tumorigenesis remains unclear. RESULTS: Here, we show histone lactylation is e...

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Detalles Bibliográficos
Autores principales:	Yu, Jie, Chai, Peiwei, Xie, Minyue, Ge, Shengfang, Ruan, Jing, Fan, Xianqun, Jia, Renbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962360/ https://www.ncbi.nlm.nih.gov/pubmed/33726814 http://dx.doi.org/10.1186/s13059-021-02308-z

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