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Review of the mechanism of cell death resulting from streptozotocin challenge in experimental animals, its practical use and potential risk to humans

Streptozotocin (STZ) (2-deoxy-2-({[methyl(nitroso)amino]carbonyl}amino)-β-D-glucopyranose) is a naturally occurring diabetogenic compound, produced by the soil bacterium streptomyces achromogenes, that exhibits broad spectrum of antibacterial properties. Streptozotocin functions as a DNA synthesis i...

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Detalles Bibliográficos
Autores principales: Eleazu, Chinedum Ogbonnaya, Eleazu, Kate Chinedum, Chukwuma, Sonia, Essien, Udeme Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962474/
https://www.ncbi.nlm.nih.gov/pubmed/24364898
http://dx.doi.org/10.1186/2251-6581-12-60