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Identification of m(6)A residues at single-nucleotide resolution using eCLIP and an accessible custom analysis pipeline
Methylation at the N(6) position of adenosine (m(6)A) is one of the most abundant RNA modifications found in eukaryotes; however, accurate detection of specific m(6)A nucleotides within transcripts has been historically challenging due to m(6)A and unmodified adenosine having virtually indistinguish...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962486/ https://www.ncbi.nlm.nih.gov/pubmed/33376190 http://dx.doi.org/10.1261/rna.078543.120 |