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Dynamic association of human Ebp1 with the ribosome

Ribosomes are the macromolecular machines at the heart of protein synthesis; however, their function can be modulated by a variety of additional protein factors that directly interact with them. Here, we report the cryo-EM structure of human Ebp1 (p48 isoform) bound to the human 80S ribosome at 3.3...

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Detalles Bibliográficos
Autores principales: Bhaskar, Varun, Desogus, Jessica, Graff-Meyer, Alexandra, Schenk, Andreas D., Cavadini, Simone, Chao, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962488/
https://www.ncbi.nlm.nih.gov/pubmed/33479117
http://dx.doi.org/10.1261/rna.077602.120