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SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms

Many individuals mount nearly identical antibody responses to SARS-CoV-2. To gain insight into how the viral spike (S) protein receptor-binding domain (RBD) might evolve in response to common antibody responses, we studied mutations occurring during virus evolution in a persistently infected immunoc...

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Detalles Bibliográficos
Autores principales: Clark, Sarah A., Clark, Lars E., Pan, Junhua, Coscia, Adrian, McKay, Lindsay G.A., Shankar, Sundaresh, Johnson, Rebecca I., Brusic, Vesna, Choudhary, Manish C., Regan, James, Li, Jonathan Z., Griffiths, Anthony, Abraham, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962548/
https://www.ncbi.nlm.nih.gov/pubmed/33831372
http://dx.doi.org/10.1016/j.cell.2021.03.027