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SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms
Many individuals mount nearly identical antibody responses to SARS-CoV-2. To gain insight into how the viral spike (S) protein receptor-binding domain (RBD) might evolve in response to common antibody responses, we studied mutations occurring during virus evolution in a persistently infected immunoc...
Autores principales: | Clark, Sarah A., Clark, Lars E., Pan, Junhua, Coscia, Adrian, McKay, Lindsay G.A., Shankar, Sundaresh, Johnson, Rebecca I., Brusic, Vesna, Choudhary, Manish C., Regan, James, Li, Jonathan Z., Griffiths, Anthony, Abraham, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962548/ https://www.ncbi.nlm.nih.gov/pubmed/33831372 http://dx.doi.org/10.1016/j.cell.2021.03.027 |
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