Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

Most human monoclonal antibodies (mAbs) neutralizing SARS-CoV-2 recognize the spike (S) protein receptor-binding domain and block virus interactions with the cellular receptor angiotensin-converting enzyme 2. We describe a panel of human mAbs binding to diverse epitopes on the N-terminal domain (NTD...

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Detalles Bibliográficos
Autores principales: Suryadevara, Naveenchandra, Shrihari, Swathi, Gilchuk, Pavlo, VanBlargan, Laura A., Binshtein, Elad, Zost, Seth J., Nargi, Rachel S., Sutton, Rachel E., Winkler, Emma S., Chen, Elaine C., Fouch, Mallorie E., Davidson, Edgar, Doranz, Benjamin J., Chen, Rita E., Shi, Pei-Yong, Carnahan, Robert H., Thackray, Larissa B., Diamond, Michael S., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962591/
https://www.ncbi.nlm.nih.gov/pubmed/33773105
http://dx.doi.org/10.1016/j.cell.2021.03.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962591/
https://www.ncbi.nlm.nih.gov/pubmed/33773105
http://dx.doi.org/10.1016/j.cell.2021.03.029

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