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Polymorphisms in the Gene Encoding Caspase 8 May Predict the Response to First-Line Platinum-Based Chemotherapy in Locally Advanced or Advanced Non-Small-Cell Lung Cancer

Caspase 8 is a protein involved in the process of cell apoptosis, which may affect the efficacy of anti-cancer treatment. The aim of our study was to determine the impact of polymorphisms in the CASP-8 gene encoding caspase 8 on the prognosis in non-small-cell lung cancer (NSCLC). The study involved...

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Detalles Bibliográficos
Autores principales: Szczyrek, Michał, Mlak, Radosław, Szudy-Szczyrek, Aneta, Kędziora, Karolina, Małecka-Massalska, Teresa, Krawczyk, Paweł, Milanowski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962636/
https://www.ncbi.nlm.nih.gov/pubmed/33800294
http://dx.doi.org/10.3390/jcm10051126