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Downregulation of Snail by DUSP1 Impairs Cell Migration and Invasion through the Inactivation of JNK and ERK and Is Useful as a Predictive Factor in the Prognosis of Prostate Cancer

SIMPLE SUMMARY: The role of dual specificity phosphatase 1 (DUSP1) in metastasis-associated processes in prostate cancer and its impact on patient outcome remains to be elucidated. Our results reveal that this phosphatase reduces Snail expression and impairs cell migration and invasion in prostate c...

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Detalles Bibliográficos
Autores principales: Martínez-Martínez, Desirée, Toledo Lobo, María-Val, Baquero, Pablo, Ropero, Santiago, Angulo, Javier C., Chiloeches, Antonio, Lasa, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962644/
https://www.ncbi.nlm.nih.gov/pubmed/33800291
http://dx.doi.org/10.3390/cancers13051158