Insight into Functional Membrane Proteins by Solution NMR: The Human Bcl-2 Protein—A Promising Cancer Drug Target

Evasion from programmed cell death (apoptosis) is the main hallmark of cancer and a major cause of resistance to therapy. Many tumors simply ensure survival by over-expressing the cell-protecting (anti-apoptotic) Bcl-2 membrane protein involved in apoptotic regulation. However, the molecular mechani...

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Detalles Bibliográficos
Autores principales: Ul Mushtaq, Ameeq, Ådén, Jörgen, Sparrman, Tobias, Hedenström, Mattias, Gröbner, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962812/
https://www.ncbi.nlm.nih.gov/pubmed/33800399
http://dx.doi.org/10.3390/molecules26051467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962812/
https://www.ncbi.nlm.nih.gov/pubmed/33800399
http://dx.doi.org/10.3390/molecules26051467

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