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Chidamide Combined With Doxorubicin Induced p53-Driven Cell Cycle Arrest and Cell Apoptosis Reverse Multidrug Resistance of Breast Cancer

The multidrug-resistant (MDR) phenotype is usually accompanied by an abnormal expression of histone deacetylase (HDAC). Given that HDAC is vital in chromatin remodeling and epigenetics, inhibiting the role of HDAC has become an important approach for tumor treatment. However, the effect of HDAC inhi...

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Detalles Bibliográficos
Autores principales: Cao, Lixia, Zhao, Shaorong, Yang, Qianxi, Shi, Zhendong, Liu, Jingjing, Pan, Teng, Zhou, Dongdong, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962870/
https://www.ncbi.nlm.nih.gov/pubmed/33738256
http://dx.doi.org/10.3389/fonc.2021.614458