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Necrostatin-1 and necroptosis inhibition: Pathophysiology and therapeutic implications
Necrostatin-1 (Nec-1) is a RIP1-targeted inhibitor of necroptosis, a form of programmed cell death discovered and investigated in recent years. There are already many studies demonstrating the essential role of necroptosis in various diseases, including inflammatory diseases, cardiovascular diseases...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962892/ https://www.ncbi.nlm.nih.gov/pubmed/33181319 http://dx.doi.org/10.1016/j.phrs.2020.105297 |