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Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

Porcine epidemic diarrhea virus (PEDV) is an alphacoronavirus responsible for significant morbidity and mortality in pigs. A key determinant of viral tropism and entry, the PEDV spike protein is a key target for the host antibody response and a good candidate for a protein-based vaccine immunogen. W...

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Detalles Bibliográficos
Autores principales: Kirchdoerfer, Robert N., Bhandari, Mahesh, Martini, Olnita, Sewall, Leigh M., Bangaru, Sandhya, Yoon, Kyoung-Jin, Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962898/
https://www.ncbi.nlm.nih.gov/pubmed/33378641
http://dx.doi.org/10.1016/j.str.2020.12.003