Cargando…

Role of ADAM10 and ADAM17 in Regulating CD137 Function

Human CD137 (4-1BB), a member of the TNF receptor family, and its ligand CD137L (4-1BBL), are expressed on immune cells and tumor cells. CD137/CD137L interaction mediates bidirectional cellular responses of potential relevance in inflammatory diseases, autoimmunity and oncology. A soluble form of CD...

Descripción completa

Detalles Bibliográficos
Autores principales: Seidel, Jana, Leitzke, Sinje, Ahrens, Björn, Sperrhacke, Maria, Bhakdi, Sucharit, Reiss, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962946/
https://www.ncbi.nlm.nih.gov/pubmed/33800462
http://dx.doi.org/10.3390/ijms22052730