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Role of ADAM10 and ADAM17 in Regulating CD137 Function
Human CD137 (4-1BB), a member of the TNF receptor family, and its ligand CD137L (4-1BBL), are expressed on immune cells and tumor cells. CD137/CD137L interaction mediates bidirectional cellular responses of potential relevance in inflammatory diseases, autoimmunity and oncology. A soluble form of CD...
Autores principales: | Seidel, Jana, Leitzke, Sinje, Ahrens, Björn, Sperrhacke, Maria, Bhakdi, Sucharit, Reiss, Karina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962946/ https://www.ncbi.nlm.nih.gov/pubmed/33800462 http://dx.doi.org/10.3390/ijms22052730 |
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